It has been known that the major cause of death and morbidity in premature infants is Necrotizing Enterocolitis and 
the treatment of this condition still uncertain remained. Until now, the standard intervention approach to patients with perforated intestine, necrotic intestine, or both is surgical resection of the involved bowel according to one of NEJM Journals on May 2006.
In line with the fact that the optimal treatment of Necrotizing Enterocolitis is uncertain, some researchers performed a multicenter randomized trial to compare intervention outcomes of primary peritoneal drainage with laparotomy and bowel resection in preterm infants with perforated necrotizing enterocolitis. The investigation tried to determine whether primary peritoneal drainage improves survival 90 days postoperatively as compared with laparotomy and resection for very-low-birth-weight (less than 1500 g) premature infants with perforated necrotizing enterocolitis.
R. Lawrence Moss, M.D. from Yale University School of Medicine, Section of Pediatric Surgery and his colleagues from multicenter universities randomly assigned 117 preterm infants (delivered before 34 weeks of gestation) with birth weights less than 1500 g and perforated necrotizing enterocolitis at 15 pediatric centers to undergo primary peritoneal drainage or laparotomy with bowel resection. For the outcome were survival at 90 days postoperatively included dependence on parenteral nutrition 90 days postoperatively and length of hospital stay.
Find the result of this investigation about Surgical Intervention for Necrotizing Enterocolitis, a Comparison Report in PDF filetype available (source: nejm.org). See also another Surgery Journal.
