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The herein article, guidelines about to support planning an effective allocation of influenza vaccine and consistent responses by states and communities regarding prevention of pandemic influenza. It concomitantly with the goal of influenza vaccination program to vaccinate all persons in the United States who choose to be vaccinated.

What you will see in the depth of the influenza vaccine article are sections discuss about General Principles and Guidance on Pandemic Vaccination, Framework for Targeting Pandemic Influenza Vaccine, Defining vaccination target groups, Guidance for Prioritizing Pandemic Vaccination as defined by PSI, and Plan for Allocation and Distribution of Vaccine to States and Communities.

Article Guideline: Allocation of Influenza Vaccine in the Role of Pandemic Influenza Prevention continued »

Herein is an Anaesthesiology Journal which described Hyperbaric Oxygen Therapy(HBOT) in association with the treatment of severe head trauma. It needs an early treatment in such prehospital phase in order to control its mortality and morbidity since traumatic brain injury has been the primary concern to the health care provider for many years.

In the depth of the article you will find sections discuss about the adequate oxygen therapy in the form of normobaric hyperoxia and hyperbaric oxygen therapy could be a promising therapy in the management of severe head injury based on the guidelines already established.

2006 Journal: Hyperbaric Oxygen Therapy (HBOT) in Severe Head Injury continued »

As already known, it is not the primary injury leads to the increased mortality for Traumatic Brain Injury (TBI) but rather evolves over the ensuing minutes, hours and days. The following journal is a guideline for the management of severe head injury in association with managing prehospital patients with severe head injuries.

The journal guideline consists of fourteen chapters of evidence-based recommendation for the patient with head injury (both prehospital and hospitalized patient issues), but it outlined on the prehospital management of severe TBI in adult and pediatric with Glasgow Coma Score (GCS) of 3 to 8.

The material of contents of this guideline are Methodology (guideline development rationale and process), Assesment (oxygenation and blood pressure, GCS, pupils), Treatment (Airway, Ventilation, Oxygenation and Fluid Resuscitation), Brain Targeted Therapy, Hospital Transport Decision, and description of the Algorithm for Prehospital Assesment and Treatment of Traumatic Brain Injury (click picture to enlarge).

Exploring Journal Guideline for the Management of TBI/Severe Head Injury continued »

Purine metabolism provides components of the nucleic acid, DNA and RNA and ATP cell’s energy. Purine catabolism resulted in a poorly soulble compound, we call it-uric acid which causes gout disease. The picture below shows you with pathways of purine metabolism.

In the following purin metabolism article you will find sections outline the genetic defects of purine metabolism, mechanism of action of select synthetic purine nucleoside analogues which particularly used in anticancer and antiviral therapeutic.

It will describe you more about the adenylsuccinate lyase deficiency (ADSL), mutation that lead to ADSL deficiency (3-5) analysis, symptoms of ADSL deficiency due to deficiency of purine, and a study article about antileukemic nucleoside within the main article.

Genetic Defects, Mechanisms, and Pathways in Purine Metabolism Article continued »