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2008 Anemia Journal: Hidroxyurea and Sickle Cell Anemia

October 28th, 2009

Pathophysiological Characteristics of Sickle Cell Anemia and the Effect of Hydroxyurea.This Anemia Journal discuss Hydroxyurea for the Treatment of Sickle Cell Anemia. The Journal was written by our respectfull Orah S. Platt, M.D. from the Department of Laboratory Medicine, Children’s Hospital Boston.

The Journal covers clinical therapeutics of Sickle Cell Anemia regarding hydroxyurea’ treatment sections such the Clinical Problem, Pathophysiology and Effect of Therapy (click picture to enlarge), Clinical evidence, Hydroxyurea Clinical Use, Adverse Effects of Hydroxyurea, Peripheral-Blood Thresholds for Adjustment of the Dose of Hydroxyurea, and Areas of Uncertainty in the Hydroxyurea treatment.

2008 Anemia Journal: Hidroxyurea and Sickle Cell Anemia continued »

Questions and Answers about MRI of the Head

October 27th, 2009

Magnetic Resonance Imaging (MRI) is a medical imaging technique used to be applied in radiology to visualize the MRI of head showing concussion internal structure and function of the body. It was found in 1973 and be used for humans in 1977 after the first human X-ray image was taken in 1895 (wikipedia.org). Herein we provide you with article consists of frequently asked question about MRI in association with the head imaging.

In this article there are several question regarding MRI of the head such as what is MRI of the head, what are some common uses of the MRI of the head procedure, what preparation for my MRI of the head, How does the procedure work, How is the MRI of the head performed, what will I experience during my MRI of the head, What benefits and risks, and the limitations of this action.

Questions and Answers about MRI of the Head continued »

The Role of D-Ribose in the Pathophysiology of Fibromyalgia and Energy Metabolism

October 26th, 2009

You are provided herein with an article contain information about Ribose in association with depressed energy levels Diagram of proposed interactions of various muscle abnormalities to pain and muscle dysfunction and/or energy recovery in fibromyalgia. According to the American College of Rheumatology, the clinical diagnosis of fibromyalgia following two criteria: 1) widespread musculoskeletal pain in all four quadrants of the body for at least three months, and 2) tenderness at 11 or more of 18 specific tender points (or trigger points) located on the upper back and chest, insides of the elbows, lower back, upper thighs and front of knees.

In the initial of the article, it discussed The Pathophysiology of Fibromyalgia, description about Energy Status of Fibromyalgic Muscle, The abnormalities of energy metabolism in fibromyalgia, clinical symptom of fatigue in association with reduced oxidative phosphorylation and ATP synthesis, then you will be taken into section discussed Ribose in Maintaining Tissue Energy Stasis, pyrophosphorylation reaction in adenine nucleotide synthesis and salvage pathways, The effect of ribose treatment in AMP deaminase deficiency.

The Role of D-Ribose in the Pathophysiology of Fibromyalgia and Energy Metabolism continued »

Psychiatry Journal: Neurobiologic Abnormalities of the Schizophrenia

October 25th, 2009

The following psychiatry journal focuses on neurobiologic abnormalities found in subjects with several type of Schizophrenia schizophrenic disorder which is based on a pathophysiologic model of relationship between schizotipal personality disorder and schizophrenia.

What you will see in this schizophrenia journal are informations such as etiologic components of schizophrenia, subjects selected to meet DSM criteria for schizotypal personality disorders (SPD), People with schizotypal personality disorder, the hypotheses of the pathophysiology of the schizophrenia based on the phenomenologic, genetic, psychophysiologic, cognitive, imaging and neurochemical studies.

Psychiatry Journal: Neurobiologic Abnormalities of the Schizophrenia continued »