In Vitro Fertilization (IVF) is a major treatment in infertility when other methods of assisted reproductive technology have failed. Researchers from University of California, Los Angeles, wrote in their journal that they have explored whether heparin and aspirin 
(H/A) in selected patients undergoing in-vitro fertilization (IVF) and embryo transfer could improve fecundity rates.
Fecundity refer to a woman’s ability to become pregnant. Normal fecundity rate in normal couples is 20-25% monthly in active trying. According to the article, patients undergo IVF and embryo transfer for infertility secondary to organic pelvic disease, ovarian dysfunction, male factor, and immunological and unexplained etiologies.
There’s speculations that led to autoimmune processes with an increased prevalence of antiphospholipid antibodies (APA) which contribute to pregnancy’s fail. Thus, this article was performed to evaluate prevalence of APA seropositivity in women with organic pelvic disease, whether APA seropositivity adversely affects implantation and pregnancy rates with IVF/embryo transfer, and whether H/A can improves ongoing clinical pregnancy rates in seropositive women who undergo IVF/embryo transfer.
Find complete article about Does Autoantibodies Really Have Impact in Fecundity in pdf file type available to be downloaded free with respects and acknowledgement to the authors (source: rialab.com, image: content.nejm.org).
