Molecular genotyping provides a rapid and reliable method for identification of common, rare and unknown a- and b-
gene mutations, which help to diagnose unexplained microcytosis and thus prevent unnecessary iron supplementation, according to one of Indian Journal of Medical Sciences published on March.
The aims of this study, accordingly, was to evaluate the frequency of α-gene, β-gene and hemoglobin variant numbers in subjects with microcytic hypochromic anemia. As we all know that Microcytic hypochromic anemia is a common condition in clinical practice, and alpha-thalassemia has to be considered as a differential diagnosis.
Fakher Rahim from Research Center of Thalassemia and Hemoglobinopathies, Physiology Research Center, Ahwaz Jondishapur University of Medical Sciences, Ahwaz, Iran studied for a total of 340 subjects from southwest part of Iran to identify the prevalence of thalassemia mutation and hemoglobin variants in unexplained microcytic anemia cases and its utility in clinical practice, with special reference to genetic counseling.
Find all information about Microcytic Hypochromic Anemia in Association with Thalasemia, a Genotype Approach in 96 Kb of PDF Format provided (source: indianjmedsci.org). See also another anemia article you may look for.
