Purine metabolism provides components of the nucleic acid, DNA and RNA and ATP cell’s energy. Purine catabolism 
resulted in a poorly soulble compound, we call it-uric acid which causes gout disease. The picture below shows you with pathways of purine metabolism.
In the following purin metabolism article you will find sections outline the genetic defects of purine metabolism, mechanism of action of select synthetic purine nucleoside analogues which particularly used in anticancer and antiviral therapeutic.
It will describe you more about the adenylsuccinate lyase deficiency (ADSL), mutation that lead to ADSL deficiency (3-5) analysis, symptoms of ADSL deficiency due to deficiency of purine, and a study article about antileukemic nucleoside within the main article.
See more about Genetic Defects, Mechanisms, and Pathways in Purine Metabolism in this purine article you can download, 425Kb, pdf filetype (source: deduveinstitute.be)
