Venereal Disease Research Laboratory (VDRL) Test is a nontreponemal serological screening for syphilis. It is a basic screening test since the screening of syphilis is dependent mainly on serological tests. VDRL test is always requested routinely accompanied with the Anti HIV serology test since syphilis screening test is routinely carried out by means of a non-treponemic reaction such as VDRL.
The following article will describe you with the principle of VDRL test, required media including VDRL antigen and VDRL slide, the procedure to perform VDRL test including quantitative and qualitative test, Cerebrospinal Fluid (CSF) VDRL test for diagnosing neurosyphilis, and the significance of VDRL test.
Screening of asymptomatic persons with the VDRL test is also can be used in the diagnosis of congenital syphilis since Positive VDRL reaction is an important cause of perinatal mortality due to infection. Hence, VDRL test plays an important role in detection syphillis cases in addition of other laboratory test.
Follow more on All about Venereal Disease Research Laboratory Test in this VDRL article (source: microrao.com)
