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Archives for Stem Cells

The Pathophysiology and Therapy of Multiple Myeloma

Multiple myeloma is a type of cancerous growth plasma cells – component of white blood cells which produces antibody in the bone marrow. Below we provide you with article about the pathophysiology and therapy of multiple myeloma.

Multiple Myeloma in a Booklet

Below we provide you with a booklet contains information especially for helping one with multiple myeloma have better understanding about the treatment of this particular disease.

Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B cell homeostasis.

The bHLH transcription factor stem cell leukemia gene (Scl) is a master regulator for hematopoiesis essential for hematopoietic specification and proper differentiation of the erythroid and megakaryocyte lineages. However, the critical downstream targets of Scl remain undefined. Here, we identified a novel Scl target gene, transcription factor myocyte enhancer factor 2 C (Mef2C) from Scl(fl/fl) [...]

Haemopoietic stem cell transplantation for children in Australia and New Zealand, 1998-2006: a report on behalf of the Australasian Bone Marrow Transplant Recipient Registry and the Australian and New Zealand Children’s Haematology Oncology Group.

OBJECTIVE: To document haemopoietic stem cell transplantation (HSCT) activity and trends among paediatric patients in Australia and New Zealand. DESIGN, SETTING AND PARTICIPANTS: A retrospective analysis of data reported to the Australasian Bone Marrow Transplant Recipient Registry by the seven paediatric HSCT institutions in Australia and New Zealand over the 9-year period 1998-2006, with particular [...]