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Archives for Coronary Artery Disease

Does Digoxin Really Have a Role in The Treatment of Heart Failure?

Digoxin has only been shown to effectively control heart rate at rest and, therefore, should only be used as a second-line therapy for heart rate control in patients with atrial fibrillation.

Cardiac Tn I Induces Severe Autoimmune Inflammation in the Myocardium

Ziya Kaya, MD and colleagues from Department of Internal Medicine III, Cardiology, University of Heidelberg, Germany took animal model experiment to study the effects on production of troponin-specific autoantibodies, cross-reactivity of autoantibodies, troponin-specific cellular response, inflammation, and expression of inflammatory cytokines, chemokines, fibrosis, heart function, ischemia/reperfusion injury, myocardial remodeling, and survival of the animals

Internal Medicine Journal : Inflammation, Atherosclerosis, and Coronary Artery Disease

Inflammation is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Recent research has shown that inflammation plays a key role in coronary artery disease (CAD) and other manifestations of atherosclerosis. As classified, inflammation can be divided into : acute and chronic. Prolonged inflammation, known as chronic [...]

Prognostic significance of small troponin I rise after a successful elective percutaneous coronary intervention of a native artery.

Cardiac troponin I is a sensitive marker of myonecrosis. Data regarding the prognostic value of troponin I increase after percutaneous coronary intervention (PCI) are conflicting. A recent American College of Cardiology/American Heart Association statement defined a troponin I increase >3 times the 99th percentile as periprocedural myocardial infarction (MI). We sought to evaluate whether or [...]